Autophagy, the process by which cells recycle damaged components, has long been associated with neuroprotection. However, the precise mechanisms by which autophagy maintains brain health have remained ...

SMAD5 expression and inhibition of the mitotic kinase aurora-A on sensitivity of breast cancer cells to chemotherapy. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This ...

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, ...

Illustration of an autophagosome (light blue double-membrane to the right) engulfing cellular material. David S. Goodsell and Daniel Klionsky/RCSB PDB-101, CC BY-SA Don’t let the textbook diagram of a ...

Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...