A newly discovered pair of stem cell lineages drives the formation of both tooth roots and the bone that anchors them. Understanding how these cells switch roles could pave the way for regenerating ...

Bone marrow is the spongy tissue located within the hollow center of bones, serving as the primary site for the continuous production of red blood cells, platelets, and white blood cells. Despite its ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...

A recent mouse model based study suggests that blocking TGF-β may improve osteoporosis treatment by helping quiescent ...

Tooth loss and bone degeneration are problems that modern medicine still struggles to fix. Data from the National Bone Health Policy Institute shows that 10 million Americans over the age of 50 have ...

Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

Bone implants often fail to fully integrate with surrounding tissue, limiting their effectiveness in regeneration. A natural but often overlooked cellular process could hold the key to better outcomes ...

A recent mouse model based study suggests that blocking TGF-β may improve osteoporosis treatment by helping quiescent osteoblasts in inactive bone surfaces return to an active state. Using spatial ...