The controlled multi-centre, randomised, prospective trial is investigating the therapy in kidney transplant recipients.

While development has been scrapped in CMV, a Phase II trial investigating the candidate in bone marrow transplant patients will continue.

Moderna said its cytomegalovirus (CMV) vaccine, mRNA-1647, failed to prevent infection in women of childbearing age in a large Phase 3 trial, prompting the company to end its congenital CMV program.

Topline results were announced from a phase 3 study evaluating Moderna’s cytomegalovirus vaccine candidate, mRNA-1647.

Declining immune responsiveness with age may be driven by changes in immune cells — not by inflammation, as previously ...

Laura Gibson is an associate professor of medicine and of pediatrics at UMass Chan Medical School. CMV belongs to the same virus family as cold sores and chickenpox and, like those viruses, lives in ...

VANCOUVER, British Columbia—Cytomegalovirus (CMV) infection in kidney or kidney/pancreas transplant recipients occurs more frequently when alemtuzumab is used for induction instead of antithymocyte ...

March 19, 2009 — Cytomegalovirus (CMV) glycoprotein B vaccine may help prevent maternal and congenital CMV infection, according to the results of a phase 2, randomized, double-blind, controlled trial ...

Cytomegalovirus (CMV) is a ubiquitous herpesvirus that, while often latent in the general population, can become reactivated in individuals with compromised immune systems. Inflammatory bowel disease ...

Human cytomegalovirus infections are still associated with severe morbidity and mortality in immunocompromised individuals, despite the availability of five drugs that are currently licensed for ...

The U.S. Centers for Disease Control and Prevention (CDC) has advised people to be wary of cytomegalovirus (CMV) during the holiday season. CMV is a common virus for people of all ages that is usually ...