Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...

Scientists have tapped into the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair (NER). This research reveals how damaged strands of DNA are repaired ...

Ultraviolet (UV) rays from sunlight can cause DNA damage that leads to skin aging and cancer. Fortunately, our bodies have a highly efficient repair system capable of swiftly identifying and repairing ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...

Scientists now recognize that spontaneous DNA errors, which we acquire in early development all the way until our last breath ...

A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or stop disease progression. Research has identified a critical DNA repair ...

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

Scientists have identified a mechanism that cells use to repair damage in DNA that is associated with aging and health conditions like cancer and ALS (also known as motor neuron disease). In this ...

Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.