Parkinson’s disease is a progressive disorder of later life, defined clinically by motor features (asymmetric bradykinesia, rigidity, tremor, and imbalance) and pathologically by neuronal degeneration ...

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, "Lipid ...

Scientists have recreated the growth of Lewy bodies in human neurons and followed their formation to gain important insight into why and how they form. Critically, they find that immune challenge is ...

Lewy bodies are a hallmark of Parkinson's disease (PD) and other related neurological conditions. Understanding why and how they develop is critical to developing better treatments. A study from The ...

Glovadalen, a novel D1 receptor positive allosteric modulator, is linked to improve OFF time in patients with Parkinson’s ...

Neural organoids derived from patient-specific iPSC lines can help open doors toward studying human brain development, physiology, and disease progression. The increased cell-cell interactions in ...

Parkinson's disease occurs when brain cells called dopaminergic neurons progressively break down, leading to a deficiency of dopamine. This dopamine deficit impairs communication between brain cells, ...

In the late 2010s, dopamine detoxing or fasting emerged as the latest scientific-sounding wellness trend. But what is a dopamine detox? The exact definition of a dopamine detox has always been ...

Parkinson’s disease (PD) is a progressive disease characterized by loss of dopaminergic neurons in the substantia nigra, which lead to motor symptoms. Aromatic-L-amino-acid decarboxylase (AADC) ...

Dopamine is a nuanced molecule that not only plays important roles in bad habits but also in behaviors that are necessary for survival and well-being. With the demonization of dopamine in recent years ...