Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the ...

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called ...

Lysosomes are thought of as cellular organelles that play an important role in recycling proteins and maintaning cells by breaking down stuff that isn’t needed. But new research has found that ...

An RNAi based genetic screen and subsequent analyses reveal how dyneins and small GTPases coordinate autophagosome positioning at the ncMTOC in fat cells, advancing understanding of autophagic vesicle ...

HHMI Janelia Research Campus Senior Group Leader Meng Wang and her team study longevity. They've shown that by overexpressing an enzyme in the lysosomes of the roundworm C. elegans, they can extend ...

Scientists have uncovered a potential new mechanism whereby α-synuclein pathology spreads. Like black holes, large densities of α-synuclein pull in surrounding matter. Among the victims trapped in ...

New research in C. elegans from scientists at Howard Hughes Medical Institute (HHMI) helps explain how changes in the parents’ lysosomes that promote longevity are transferred to their offspring.

October 24, 2025) Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate ...