Before tangles kill neurons, tau-linked transport defects may be reversible

Neurons, specialized cells that transmit information across the nervous system, communicate with each other via projections ...
C&EN

SARM1 inhibitors enter clinical trials for ALS, neuropathy

Blocking the NAD hydrolase may save axons from neurodegeneration, if researchers can figure out a safe way to do it ...
Medical Xpress

Study unveils mechanisms driving axonal accumulation of TDP-43 and associated nerve damage in ALS

A creative cartoon depicting firefighters symbolizing muscle-derived exosomes loaded with neuroprotective miR-126. They are shown spraying water balloons onto a neuromuscular junction to extinguish ...
The Scientist

Challenging the Axon’s Classic Shape

Axons are the brain’s information highways, transporting cellular cargo, chemical signals, and electrical impulses to other cells. These “roads” are typically depicted as smooth and cylindrical, with ...