An essential component of living cells, the nucleolus underwent a major evolutionary shift around 300m years ago. Scientists have solved an age-old mystery in biology by discovering a protein found in ...

The size of a cell's nucleolus may reveal how long that cell, or even the organism it belongs to, will live. Over the past few years, researchers have been piecing together an unexpected link between ...

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus. Inside ...

At most, 10 people in the world are known to have BPTA. Five of them participated in the current study, and they were found to share virtually the same mutation in the gene for the HMGB1 protein. It ...

Knowing when you’re going to die is a fact best left unexplored. But for better or for worse, scientists have discovered a part of human cells that is tightly linked to the aging process, and it may ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

Ageing researchers have long been searching for so-called biomarkers of ageing, which allow predictions about health and lifespan of organisms. Varnesh Tiku, a scientist in the department of Director ...

Proposing a potential mechanism for C9ORF72-based amyotrophic lateral sclerosis and frontotemporal dementia in Science online July 31, researchers report that repeat dipeptides made by the mutant gene ...

Damaging a cell's nucleolus could eliminate cancer cells by raising the levels of a crucial tumour prevention protein, experts have said. Scientists from the University of Liverpool have observed that ...

THE nucleolus was first figured in 1781 as a spot in the centre of a round or oval body (the nucleus) in epithelial cells of the eel. Since then it has been described in the nuclei of almost every ...