The cell is understood to be highly organized, with specialized areas for different functions and molecular motors shuttling components around. Researchers from the University of Illinois' Chicago and ...

A new study has revealed that the gene HMGN1 is a key driver of congenital heart defects (CHDs) in Down syndrome. Using ...

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion. This allows specific regions to come into contact and thereby activate a gene. A ...

Three copies of chromosome 21 cause Down syndrome (DS), and roughly half of children born each year in the United States with ...

Genomes contain the complete library of information required to build and maintain a living organism—the figurative blueprints of life. In eukaryotes, genomes are stored in the nuclei, where they are ...

Using computer simulations, chemists have discovered how nuclear bodies called nucleoli interact with chromosomes in the nucleus, and how those interactions help the nucleoli exist as stable droplets ...

Within the hallowed walls of the cell, conflict simmers; a tenuous peace, and perhaps its very survival, rest on the slimmest of margins. Housed within the cell’s inner sanctum – the nucleus – is its ...

Researchers have discovered key mechanisms and structural details of a fundamental biological process -- how a cell nucleus and its chromosomal material reorganizes itself after cell division. The new ...

Clubroot disease, caused by Plasmodiophora brassicae, is a devastating soil-borne pathogen that severely threatens global ...

The information of the human genome is encoded by approximately 3 billion DNA base pairs and packaged into 23 pairs of chromosomes. If all chromosomes could be disentangled and linearly aligned, they ...

Gene transfers from chloroplasts to the nucleus occur naturally over evolutionary time scales but have always been inferred from sequence comparisons, never directly observed. A notable new report has ...