The study of electrophysiology began in the 18 th century with Luigi Aloisio Galvani’s pioneering experimental discovery. The legs of a dead frog could be induced to twitch when a small electric shock ...

Manual patch clamping requires considerable skill and experience due to the technically challenging setup requirements, and as such, only allows recording of a small sample of cells (approximately ...

The patch-clamp electrode is valued for its high-sensitivity intracellular recording that can measure not only propagation of action potentials (APs) in neurons but also subthreshold events such as ...

Neuronal cells are required for modeling human degenerative and genetic diseases, for example Alzheimer’s, Parkinson’s, and Huntington's diseases, as well as neurotoxic effects 1,2. In research, the ...

Electrophysiology is the measurement of the electrical activity, or “excitability”, of biological cells (be they muscle cells, neurons, or stem cells). This can be done at a single-cell level, or it ...