Podocytes are highly specialised epithelial cells that wrap around the glomerular capillaries and form the final layer of the glomerular filtration barrier. Their interdigitating foot processes and ...

Although the pathophysiology of mesangial cells has long been considered to be the major factor in the development of glomerulosclerosis in type 1 or type 2 diabetes, more recent evidence suggests ...

Podocyte-specific targeting of OTUD5 alleviates diabetic kidney disease July 10, 2024 ...

Senior Postdoctoral Research Fellow, GOFARR Laboratory for Organ Regenerative Research and Cell Therapeutics in Urology, Children's Hospital Los Angeles The glomerular filtration barrier, generated ...

The kidneys are vital organs that sustain life by filtering the blood and producing urine. This filtration process takes place in specialized structures called glomeruli, where podocytes play a ...

A single podocyte was reconstructed in three dimensions based on serial glomerular section images obtained by array tomography. The three-dimensional reconstruction enabled quantitative volume ...