As genomic databases expand and artificial intelligence tools advance, there is a growing demand for efficient characterization of large numbers of proteins. To this end, here we describe a ...
Top-down analysis of intact proteins and middle-down analysis of proteins subjected to limited digestion require efficient detection of traces of proteoforms in samples, necessitating the reduction of ...
Creating analytical tools that support the advancement of knowledge can often come about through the integration of existing information and techniques, theoretical and practical, directed toward a ...
Effective and efficient protein purification processes are essential in drug discovery and development. Affinity fusion tags are commonly used in protein purification due to their ability to enable ...
Vortex fluidic devices (VFDs) used with immobilized metal affinity chromatography (IMAC) have provided an effective, albeit cumbersome, way to separate His-tagged proteins. Researchers recently ...
Scientists can choose from many protein purification protocols, but some methods fail to produce sufficient sample purity. By selecting the right chromatography method, researchers can optimize the ...