A cell is a complex environment in which substances (metabolites) must maintain a correct state of equilibrium, which may vary depending on specific needs. Cells can maintain the proper concentrations ...

Riboswitches are RNA segments that switch genes on and off, either during DNA transcription or during protein translation, but little is known about the precise workings of this process. A new study ...

Guanine-sensing riboswitches are RNA genetic control elements that modulate gene expression in response to changing concentrations of guanine 1. They represent one of several classes of ...

Many bacteria have molecular control elements via which they can switch genes on and off. These riboswitches also open up new options in the development of antibiotics or the detection and ...

Scientific discoveries come through many different means. Breakthroughs can result from purposefully-executed research projects that are perhaps punctuated with unexpected flashes of insight. In rare ...

How does an organism know when it must produce a protein and in what amount? Michael Famulok and his team at the University of Bonn have now taken a meaningful step toward a better understanding of ...

In a recent study, researchers developed a low-cost RNA-based sensor that detects biomarker proteins. Researchers at Penn State University (PA, USA) have engineered an RNA-based sensor, a riboswitch, ...

Drug-resistant bacteria are a growing challenge to world health, and new approaches to antibiotic development are needed. Riboswitches, regulatory elements of mRNA, are shown to be a potential new ...

This kind of complex signaling had long been thought to be the domain of just proteins. A team of researchers at The Scripps Research Institute has found that RNA riboswitches respond simultaneously ...

As long-trusted antibiotics encounter increased resistance by the bacterial pathogens they were originally designed to kill, the need for novel anti-infective drug treatments is mounting. One young ...

A cell is a complex environment in which substances (metabolites) must maintain a correct state of equilibrium, which may vary depending on specific needs. Cells can maintain the proper concentrations ...