Use of insulin or sulfonylureas as second-line treatment in adults with type 2 diabetes is associated with increased cardiovascular risk, whereas use of newer classes of glucose-lowering drugs is not, ...

This article was originally on a blog post platform and may be missing photos, graphics or links. See About archive blog posts. Sulfonylureas, the first family of oral drugs used for treating type 2 ...

Neonatal diabetes can result from mutations in either Kir6.2 or SUR1 subunits of the pancreatic potassium ATP channel, which disrupt insulin release. Sulfonylureas close these channels and restore ...

Sulfonylureas are an older class of type 2 diabetes therapy but remain the most commonly prescribed antidiabetic drug after metformin. Patients taking metformin for type 2 diabetes (T2D) who switch to ...

People with type 2 diabetes treated with metformin plus a sulfonylurea with high affinity for cardiac mitochondrial adenosine triphosphate–sensitive potassium (mitoK ATP) channels, such as glyburide ...

Insured, adult patients with type 2 diabetes that received sulfonylureas or basal insulin as a second-line antidiabetic medication therapy were at increased risk for certain CV events, according to ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Back to Healio Lean older adults with type 2 diabetes ...

The subjects of the study were 228 diabetic children, 104 boys and 124 girls. All were under sixteen years of age. With few exceptions, all were in summer camps for diabetic children and leading ...

The researchers found that the weighted incidence rate was 51.90 and 58.41 per 100,000 person-years in individuals initiating SGLT-2 inhibitors and sulfonylureas, respectively.

Type 2 diabetes patients starting on SGLT2 inhibitors had a sightly lower risk of autoimmune rheumatic diseases compared with ...

Sitagliptin (trade names: Januvia and Xelevia) is approved for certain adults with type 2 diabetes mellitus whose blood-glucose levels are inadequately controlled by diet and exercise alone. The fixed ...

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of ...