Researchers have developed a method to program the spatial organization of double-stranded DNA by incorporating Hoogsteen interactions. Researchers at Aarhus University (Denmark) have developed a ...

Natural DNA is often double-stranded. Yet, there exists another, lesser-known class of interactions between DNA. These so-called normal or reverse Hoogsteen interactions allow a third strand to join ...

(Nanowerk News) A human cell harbors roughly 2 meters of DNA, encompassing the essential genetic information of an individual. If one were to unwind and stretch out all the DNA contained within a ...

Figure 2: New research shows that by using a new method called triplex origami one can create triple DNA helices that can bend or "fold" DNA in into compact structures. Illustr: Minke A. D. Nijenhuis ...

A new method for recognizing and targeting DNA that dramatically expands the range of genetic sequences scientists can identify has been developed by experts at the University of Portsmouth. Published ...

Figure 3: Triplex-mediated folding of dsDNA, a) A dsDNA sequence containing triplex-forming domains (coloured) is folded by four TFO strands, i.e. single-stranded DNA acting as staples, into a hairpin ...