In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers at the University of Basel have now discovered that these skeletal cells do not just ...

The first "blueprint" of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone ...

Skeletal stem cells (SSCs) and related progenitors with osteogenic potential, collectively termed skeletal stem and/or progenitor cells (SSPCs), are crucial for providing osteoblasts for bone ...

The From Labs to Lives Blog connects everyday topics with UC Davis research. Each post is reviewed by our experts, ensuring you always get useful information you can trust. Because we can’t see them, ...

Bone development and bone remodelling during adult life are highly anabolic processes requiring an adequate supply of oxygen and nutrients. Bone-forming osteoblasts and bone-resorbing osteoclasts ...

This illustration shows the major cell types affected by cellular senescence in various skeletal diseases. As the body ages, senescent cells accumulate in different tissues—including bone, cartilage, ...

Constructed image from spatial transcriptomics slides measuring gene expression in tissues. This shows the developing upper limb, including the developing hand and digits. Each spot represents a ...