This is a preview. Log in through your library . Abstract Many peptide hormones are synthesized as larger precursors which undergo endoproteolytic cleavage at paired basic residues to generate a ...
The secretory pathway in eukaryotic cells is crucial for maintaining cellular function and physiological activities, as it ...
Protein trafficking is a fundamental cellular process that ensures efficient sorting, modification, and delivery of proteins to their correct subcellular destinations. At its core, this process ...
The transport of pro-alpha-factor from the ER to the Golgi apparatus in gently lysed yeast spheroplasts is mediated by diffusible vesicles. These transport vesicles contain core-glycosylated pro-alpha ...
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Glycerol reveals previously overlooked connections between intracellular metabolism and vesicle transport
Prof. Fang-Jen S. Lee's team at National Taiwan University has discovered that an intermediate cellular metabolism molecule, glycerol, regulates the localization and function of the Golgi protein Imh1 ...
Identified more than 100 years ago by Camillo Golgi, the Golgi is a series of flattened cisternae that acts as a critical sorting and processing station for intracellular traffic. It receives cargo in ...
In eukaryotic cells, many new proteins begin life in an organelle known as the endoplasmic reticulum (ER). From there, they are taken to the side of the Golgi apparatus (Fig. 1) facing the ER (the cis ...
Dr. Guangyu Wu is dissecting the molecular homing that enables a nascent protein to ultimately find its way to the surface of a cell as a mature receptor type that helps us taste, smell and even ...
A recent study by a group of scientists has revealed that a different mechanism is responsible for the formation and maintenance of the cell organelle called endosome that sorts and distributes ...
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