An RNAi based genetic screen and subsequent analyses reveal how dyneins and small GTPases coordinate autophagosome positioning at the ncMTOC in fat cells, advancing understanding of autophagic vesicle ...

Scientists at the (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed to act as a motor ...

The 15th annual Les Turner Symposium on ALS will be held on Monday, Nov. 3, 2025 in Chicago. Hosted by the Les Turner ALS ...

Explore the unique issues of rare disease trials and how “gene silencing” therapies could reshape the future for patients ...

Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed to act as a motor dragging chromosomes into place during cell division, in ...

An international research team, led by Shinghua Ding at the University of Missouri, has identified a previously unknown ...

The paper, “ Intrinsically accelerated cellular degradation is amplified by TDP-43 loss in ALS-vulnerable motor neurons in a zebrafish model ,” suggests that the cellular degradation load linked to ...

Researchers identified a protein in mouse models that acts as a brake on myelin production, which could be a target for new MS treatments.

Standard MRI scans of a person's tongue could assist in the early detection and ongoing monitoring of motor neuron disease.

Researchers showed that large motor neurons face high metabolic stress, making them more prone to degeneration. Reducing this ...