Nature

Nucleolar Arf sequesters Mdm2 and activates p53

The Ink4a/Arf locus encodes two tumour-suppressor proteins that are specified in part by the unprecedented use of alternative reading frames within a common second exon of both genes 1. The first ...
Frontiers

Case Report: Gastric and duodenal metastasis of malignant melanoma: a rare clinical presentation

Background: Malignant melanoma represents one of the most common sources of metastatic tumors to the gastrointestinal (GI) tract. However, synchronous involvement of both the stomach and duodenum is ...
Frontiers

Acetaldehyde and methylglyoxal: comparative analysis of toxic electronic cigarette degradation products in 3D and 2D exposure systems using human bronchial epithelial models

1 Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA, United States 2 UCR Proteomics Core, University of California, Riverside, Riverside, CA, United ...
eLife

Explainable machine learning-assisted exploration of chromatin dynamics reveals chromosome-specific response to serum starvation

This interesting study adapts machine learning tools to analyze movements of a chromatin locus in living cells in response to serum starvation. The machine learning approach developed is useful, the ...
C&EN

Machine Learning-Guided Prediction of Formulation Performance in Inhalable Ciprofloxacin–Bile Acid Dispersions with Antimicrobial and Toxicity Evaluation

School of Pharmacy, University of Reading, Reading RG6 6AD, U.K. Department of Anaesthesia, College of Health Sciences, Cihan University-Sulaimaniya, Sulaymaniyah, Kurdistan Region 46001, Iraq ...