The 49ers have yet to open the practice window for Brandon Aiyuk to return, which should start to set in a harsh reality.

Defensive coordinator Robert Saleh has made some recent strategic changes that have allowed the defense to play more ...

The bottom line is that the 49ers have positioned themselves to play in the postseason, though they’ve cooled off of late and ...

For the 49ers, Ricky Pearsall remained a non-participant, missing practice once again. Brock Purdy was limited for the second ...

WOODLAND HILLS, Ca. On Thursday, the Los Angeles Rams continued their preparations as they get set to take on the San ...

San Francisco 49ers running back Christian McCaffrey (23) stiff-arms New York Giants cornerback Andru Phillips (22) during ...

When the San Francisco 49ers lost another key defensive player for the season when rookie Mykel Williams went down with a ...

San Francisco 49ers general manager John Lynch explained the team's inactivity on Tuesday's NFL trade deadline.

The San Francisco 49ers have heavily relied on young defenders so far this year, and cornerback Upton Stout has been one of ...

Colin Cowherd on Kyle Shanahan: “My Coach of the Year is Kyle Shanahan. He’s winning with peanut brittle, baling wire and ...

Sunday, in the media room at MetLife Stadium, where the New York Jets, the New York Giants and NFL players’ ACLs go to die ...

Using data from Pro-Football-Reference.com, Stacker compiled a list of the biggest comeback wins in San Francisco 49ers ...