Explore the unique issues of rare disease trials and how “gene silencing” therapies could reshape the future for patients ...

Parkinson's disease is a neurodegenerative disorder that affects movement, and there is no cure. But there are ways to lower ...

Research on Parkinson’s is revealing several risk factors related to our lifestyles and environment, and you can act on some ...

Social hierarchies are everywhere-think of high school dramas, where the athletes are portrayed as most popular, or large ...

Fallah and colleagues characterize the connectivity between two basal ganglia output nuclei, the SNr and GPe, and a the pedunculopontine nucleus, a brainstem nucleus that is part of the mesencephalic ...

Google dubbed an error from its Med-Gemini model a typo. Experts say it demonstrates the risks of AI in medicine. Google dubbed an error from its Med-Gemini model a ...

Neurons deep in the brain not only help to initiate movement -- they also actively suppress it, and with astonishing precision. The findings are especially relevant for better understanding ...

University of Arizona researchers have revealed new insights into the neurobiological cause of the involuntary, uncontrollable movement disorders that develop in patients with Parkinson’s disease (PD) ...

The existence of direct projections between the globus pallidus externa (GPe) and the cortex places the GPe in a new light as an input/output region of the basal ganglia, rather than an inhibitory ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. Fallah and colleagues ...

Objectives Chorea, characterised by involuntary, irregular movements, is a rare neurological manifestation of antiphospholipid syndrome (APS). The specific clinical features remain unclear. This study ...