Commercially launched in the U.S. in November 2025, TONMYA (cyclobenzaprine HCl sublingual tablets) for long-term daily dosing at bedtime is the first new FDA-approved treatment for fibromyalgia in ad ...

Three-dimensional imaging has revealed that nerve fibres actively collaborate with tumour-associated fibroblasts at the earliest stages of pancreatic cancer, creating a self-reinforcing ...

Mewgenics, the cat-breeding tactics roguelike from the developer of The Binding of Isaac, has hit the ground running to say the least. It’s already made back the cost of its roughly seven-year ...

The launch has been so successful that Glaiel has confirmed that all development costs for the roguelite were recouped within three hours of the game being on sale. It is, perhaps surprisingly, a ...

TL;DR: Mewgenics, a unique turn-based RTS by Binding of Isaac creator Edmund McMillen, quickly became Steam's #1 best-seller, recouping its development budget within hours. Its innovative cat-breeding ...

A dense, detailed, and hugely varied strategy roguelike, Mewgenics borrows much from its iconic predecessor with an imaginative and rewarding gameplay loop. Occasionally harsh RNG can be a buzzkill, ...

Indie game developer Edmund McMillen hosted a Reddit AMA today offering some more details about his upcoming game Mewgenics. For starters, the Steam release date for this turn-based cat-breeding RPG ...

Publisher Nicalis and developer Edmund McMillen announced The Binding of Isaac: Repentance+ will launch for the Nintendo Switch 2 in Q1 2026. A physical edition will be available for $69.99 on the ...

You don’t have to go it alone. Experience The Binding of Isaac‘s devious blend of dungeon crawling, twin-stick shooter action and endlessly randomized replayability like never before: with friends ...

Chris has been playing video games for most of his life, and writing about them off-and-on for a significant chunk of that time. He has also gotten involved with the industry more directly by working ...

Ashely Claudino is an Evergreen Staff Writer from Portugal. She has a Translation degree from the University of Lisbon (2020, Faculty of Arts and Humanities). She has been writing for Game Rant since ...