C HARLOTTE, N.C. -- The Carolina Panthers ' locker room was in shock on October 20, 2022, when star running back Christian McCaffrey was traded to the San Francisco 49ers.

The Carolina Panthers may have to dig even deeper in the middle of the defense.

The Carolina Panthers are 6-5 heading into Week 12, a statement we didn't think we'd be able to make at several points this year. But through it all, they remai

Rohit Ponnaiya breaks down his early Panthers vs. 49ers predictions ahead of Monday Night Football in Week 12. Free NFL picks for November 24.

Every game matters from here on out for the San Francisco 49ers, who improved to 7-4 after Sunday's decisive 41-22 win over the Arizona Cardinals. The 49ers now turn their attention to a Monday Night Football showdown against the Carolina Panthers before facing the Cleveland Browns and entering their long-awaited bye week.

But beating the 49ers, or the Seahawks/Rams if the Panthers decide to get a massive upset, is the best thing to do to get closer to the playoffs. This article was originally published on www.si.com/nfl/panthers/onsi as Despite brutal slate, insider claims Panthers 'control' their playoff destiny.

The Bills are six-point favorites in the latest Bills vs. Buccaneers odds at SportsLine, and the over/under for total points scored is 45.5. Buffalo is a -288 money line favorite (risk $288 to win $100),

The Atlanta Falcons have released a new depth chart ahead of their Week 12 matchup against the New Orleans Saints. With Michael Penix Jr. on the injured reserve list, Kirk Cousins has taken over as the team's starting quarterback.